Magnesium Bisglycinate

About Magnesium Bisglycinate

An important mineral involved in more than 600 of the body’s enzymatic reactions

The mineral magnesium is crucial for the body to function properly because magnesium is involved in more than 600 of the body's enzymatic reactions.* The compound magnesium bisglycinate is also called magnesium glycinate. However, because it has two glycine molecules attached, it is more accurately called “bisglycinate” (bis = two). Two separate glycine molecules occupy an active site on each magnesium molecule, leading to superior absorption because of increased solubility.

The Thorne Difference

The bisglycinate form of magnesium has superior absorption because of increased solubility. A crossover study found that serum levels of magnesium over eight hours were highest for magnesium bisglycinate, followed by dimagnesium malate; least absorbed was magnesium oxide. The improved absorption and solubility is because glycine decreases the pH of the intestines.

The glycine also takes up space on the magnesium molecule, which decreases the propensity of the magnesium to complex with plant-based phytates that would otherwise interfere with its absorption. Because glycine takes up active sites on the molecule, less water attaches to the molecule, which reduces the laxative effect typically seen with magnesium compounds.

Products with Magnesium Bisglycinate

Magnesium Bisglycinate - Travel Packs

Bone & Joint, Heart & Vessels, Sleep, Sports Performance

$46

(5/5)

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Bone & Joint, Heart & Vessels, Sleep, Sports Performance

$47

Basic Nutrients 2/Day - NSF Certified for Sport

Multivitamins, Sports Performance

$38

(5/5)

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Multivitamins, Sports Performance

$40

The Science

Sports Performance

Magnesium status and the physical performance of volleyball players: effects of magnesium supplementation.. Journal of Sport Sciences. 2014;32(5):438-445.. Setaro L, Santos-Silva P, Nakano E, et al.

Cardiovascular Support

Role of magnesium in cardiovascular diseases.. Cardiology in Review. 2014 Jul-Aug; 22(4):182-92. Kolte D, Vijayaraghavan K, Khera S, et al.

Serum magnesium…in men: The Kuopio Heart Disease Study.. European Journal of Epidemiology. 2016 Oct: 31(10):1035-1043 . Kunutsor S, Khan H, Laukkanen J.

Oral magnesium supplementation improves endothelial function and attenuates subclinical…women.. Journal of Hypertension. 2017 Jan; 35(1):89-97. Cunha A, D'El-Rei J, Medeiros F, et al.

Bone and Muscle Support

Dietary magnesium intake, bone mineral density and risk of fracture: a systematic review and meta-analysis.. Osteoporosis International. 2016 Apr; 27(4):1389-1399.. Farsinejad-Marj M, Saneei P, Esmaillzadeh A.

Dietary magnesium is positively associated with skeletal muscle power and indices of muscle mass and may attenuate the association between circulating C-reactive protein and muscle mass in women.. Journal of Bone and Mineral Research. 2016 Feb; 31(2):317-325.. Welch A, Kelaiditi E, Jennings A, et al.

Metabolic Syndrome Support

Dose-response relationship between dietary intake of magnesium…: a systematic review and meta-regression analysis of prospective cohort studies.. Nutrients. 2016;8(11). pii: E739.. Fang X, Han H, Li M, et al.

Magnesium intake and incidence of metabolic syndrome among young adults.. Circulation. 2006;113:1675-1682.. He K, Liu K, Daviglus M, et al.

Absorption and Bioavailability

Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection.. JPEN J Parenter Enteral Nutr 1994;18(5):430-435.. Schuette SA Lashner BA, Janghorbani M.

Women’s Health

Clinical significance of low serum magnesium in pregnant women attending the University of Benin Teaching Hospital.. Nigerian Journal of Clinical Practice. 2013;16(4):448-453.. Enaruna N, Ande A, Okpere E.

Women's Health

Magnesium supplementation…in pregnancy: a randomized placebo-control trial.. Archives of Gynecology and Obstetrics. 2013;288(6):1269-1274.. Bullarbo M, Ödman N, Nestler A, et al.

Respiratory Support

Oral magnesium supplementation in children… a double-blind, randomized, placebo-controlled crossover trial. . Am J Clin Nutr 2012;96:50-56.. Gontijo-Amaral C, Guimaraes EV, Camargos P.

Our Ingredients

Thorne cares deeply about where our ingredients come from. Our research and development team is tasked with sourcing exceptional ingredients, maintaining oversight of an ingredient's origin, and providing complete supply chain transparency.

We partner only with suppliers whose practices emphasize quality, science, and environmental responsibility. We believe that better ingredients mean better potency, absorption, and digestibility - and ultimately better health.

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